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CHS-828 (GMX1778)


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产品目录号: A12515


产品名 目录号 价格 数量
CHS-828 5mg A12515-5
¥ 500.00
CHS-828 10mg A12515-10
¥ 700.00
CHS-828 25mg A12515-25
¥ 1,500.00



CHS-828 is a potent inhibitor of NAD+ biosynthesis enzyme NAMPT with IC50 <25 nM.

CHS-828 (GMX1778)




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Chemical Information

目录号 A12515
Mechanism of action Inhibitor
分子量 371.86
化学分子式 C19H22ClN5O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 200484-11-3
Synonyms GMX1778, GMX-1778, GMX 1778, CHS828, CHS 828
化学名称 (Z)-2-(6-(4-chlorophenoxy)hexyl)-1-cyano-3-(pyridin-4(1H)-ylidene)guanidine


CHS-828 is a potent inhibitor of NAD+ biosynthesis enzyme NAMPT with IC50 <25 nM.
25 nM120 nM(Kd)


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.89 mL 134.46 mL 268.92mL
0.5 mM 5.38 mL 26.89 mL 53.78 mL
1 mM 2.69 mL 13.45 mL 26.89 mL
5 mM 0.54 mL 2.69 mL 5.38 mL

*The above data is based on the productmolecular weight 371.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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