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Chemical Information
| 目录号 | A12515 |
|---|---|
| Mechanism of action | Inhibitor |
| 分子量 | 371.86 |
| 化学分子式 | C19H22ClN5O |
| Solubility | DMSO |
| 纯度 | >98% |
| 储存方式 | at -20°C 2 years |
| CAS No. | 200484-11-3 |
| Synonyms | GMX1778, GMX-1778, GMX 1778, CHS828, CHS 828 |
| SMILES code | ClC1=CC=C(OCCCCCC/N=C(\N=C2C=CNC=C/2)NC#N)C=C1 |
| 化学名称 | (Z)-2-(6-(4-chlorophenoxy)hexyl)-1-cyano-3-(pyridin-4(1H)-ylidene)guanidine |
Description |
CHS-828 is a potent inhibitor of NAD+ biosynthesis enzyme NAMPT with IC50 <25 nM. | ||||||||||
Targets |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.89 mL | 134.46 mL | 268.92mL |
| 0.5 mM | 5.38 mL | 26.89 mL | 53.78 mL |
| 1 mM | 2.69 mL | 13.45 mL | 26.89 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.38 mL |
*The above data is based on the productmolecular weight 371.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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