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CHS-828 (GMX1778)

NAMPT 抑制剂

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产品目录号: A12515

库存状态:中国现货中国现货

产品名 目录号 价格 数量
CHS-828 5mg A12515-5
¥ 500.00
CHS-828 10mg A12515-10
¥ 700.00
CHS-828 25mg A12515-25
¥ 1,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

CHS-828 is a potent inhibitor of NAD+ biosynthesis enzyme NAMPT with IC50 <25 nM.

CHS-828 (GMX1778)

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Chemical Information

目录号 A12515
Mechanism of action Inhibitor
分子量 371.86
化学分子式 C19H22ClN5O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 200484-11-3
Synonyms GMX1778, GMX-1778, GMX 1778, CHS828, CHS 828
SMILES code ClC1=CC=C(OCCCCCC/N=C(\N=C2C=CNC=C/2)NC#N)C=C1
化学名称 (Z)-2-(6-(4-chlorophenoxy)hexyl)-1-cyano-3-(pyridin-4(1H)-ylidene)guanidine

生物活性

Description
CHS-828 is a potent inhibitor of NAD+ biosynthesis enzyme NAMPT with IC50 <25 nM.
Targets
NAMPT NAMPT
25 nM120 nM(Kd)

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.89 mL 134.46 mL 268.92mL
0.5 mM 5.38 mL 26.89 mL 53.78 mL
1 mM 2.69 mL 13.45 mL 26.89 mL
5 mM 0.54 mL 2.69 mL 5.38 mL

*The above data is based on the productmolecular weight 371.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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