CI994 (Tacedinaline)
目录号: A11964
HDAC 抑制剂
CI-994 是一种组蛋白去乙酰化酶(HDAC)抑制剂,能在活细胞中诱导组蛋白超乙酰化。
| Discription | CI-994 is a histone deacetylase (HDAC) inhibitor and induces histone hyperacetylation in living cells. | |||||
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| 目录号 | A11964 |
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| 分子式 | C15H15N3O2 |
| 分子量 | 269.3 |
| CAS号 | 112522-64-2 |
| SMILES | CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N |
| 其他名称 | CI-994, CI 994, Acetyldinaline, Goe 5549, G? 5549. PD 123654 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 51 mg/mL (189.37 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+40% PEG 300+ddH2O | 4 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.13 mL | 185.67 mL | 371.33 mL |
| 0.5 mM | 7.43 mL | 37.13 mL | 74.27 mL |
| 1 mM | 3.71 mL | 18.57 mL | 37.13 mL |
| 5 mM | 0.74 mL | 3.71 mL | 7.43 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2