Cilengitide trifluoroacetate

目录号: A12371

Integrin inhibitor

Cilengitide trifluoroacetate Chemical Structure

CAS NO. 199807-35-7

Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.

库存: 现货

规格 价格 数量
5 mg
¥ 1,500.00
10 mg
¥ 2,000.00
25 mg
¥ 3,500.00
50 mg
¥ 6,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
靶点信息
αvβ3 receptor (Cell-free assay) αvβ5 receptor (Cell-free assay)
4.1 nM79 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.23 mL 71.15 mL 142.31 mL
0.5 mM 2.85 mL 14.23 mL 28.46 mL
1 mM 1.42 mL 7.12 mL 14.23 mL
5 mM 0.28 mL 1.42 mL 2.85 mL

*The above data is based on the productmolecular weight 702.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12371
MECHANISM OF ACTION Inhibitor
M. Wt 702.7
Formula C29H41N8O9F3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 199807-35-7
Synonyms EMD 12197,EMD-85189,EMD-121974,NSC-707544,D03497
SMILES CC(C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N1C)Cc2ccccc2)CC(=O)O)CCCNC(=N)N.C(=O)(C(F)(F)F)O

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