Cilengitide trifluoroacetate

Name: Cilengitide trifluoroacetate
SKU: A12371
Price: 525 CNY
Rating: 5 (1 reviews)

目录号: A12371

Integrin 抑制剂

1 篇发表文献

Cilengitide 是一种环状 Arg-Gly-Asp 肽，具有潜在的抗肿瘤活性。Cilengitide 结合并抑制 alpha(v)beta(3) 和 alpha(v)beta(5) 整合素的活性，从而抑制内皮细胞间的相互作用、内皮细胞与基质的相互作用以及血管生成。

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规格	价格	库存
5mg	¥525.00	现货
10mg	¥945.00	现货
25mg	¥1,785.00	现货
50mg	¥2,905.00	现货
100mg	¥5,110.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Cilengitide trifluoroacetate发表的1篇文献

Yi Han Tan, .et al. , Cell Microbiol, 2017, Aug;19(8) PMID: 28186697

生物活性

Discription

Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.

Targets

Target	Value

产品信息

目录号	A12371
分子式	C29H41N8O9F3
分子量	702.7
CAS号	199807-35-7
SMILES	CC(C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N1C)Cc2ccccc2)CC(=O)O)CCCNC(=N)N.C(=O)(C(F)(F)F)O
其他名称	EMD 12197,EMD-85189,EMD-121974,NSC-707544,D03497
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	89 mg/mL (126.66 mM)
	Water	7 mg/mL (9.96 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.23 mL	71.15 mL	142.31 mL
0.5 mM	2.85 mL	14.23 mL	28.46 mL
1 mM	1.42 mL	7.12 mL	14.23 mL
5 mM	0.28 mL	1.42 mL	2.85 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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