Cilengitide

Name: Cilengitide
SKU: A12372
Price: 280 CNY
Rating: 5 (6 reviews)

目录号: A12372

Integrin 抑制剂

6 篇发表文献

Cilengitide 是一种环状 Arg-Gly-Asp 肽，具有潜在的抗肿瘤活性。Cilengitide 通过结合并抑制 alpha(v)beta(3) 和 alpha(v)beta(5) 整合素的活性，从而抑制内皮细胞间的相互作用、内皮细胞与基质的相互作用以及血管生成。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥385.00	现货
5mg	¥630.00	现货
10mg	¥1,085.00	现货
25mg	¥1,960.00	现货
50mg	¥3,185.00	现货
100mg	¥4,620.00	现货
*10mM 1mL in DMSO**	¥910.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Cilengitide发表的6篇文献

Marion Bouvet, .et al. , Sci Rep, 2020, 10: 11404 PMID: 32647159

Rosalie Richards, .et al. , bioRxiv, 2018, 15 Oct 2018

Hiroki Kanazawa, .et al. , PLoS One, 2017, 12(2): e0173051 PMID: 28235037

Yasuda J, .et al. , Naunyn Schmiedebergs Arch Pharmacol, 2017, Nov;390(11):1135-1144 PMID: 28785775

Yasuda J, .et al. , Eur J Pharmacol, 2017, Jul 15;807:64-70 PMID: 28457922

Hsian-Yu Wang, .et al. , Onco Targets Ther, 2016, 9: 2961-2973 PMID: 27284246

生物活性

Discription

Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12372
分子式	C27H40N8O7
分子量	588.66
CAS号	188968-51-6
SMILES	CC(C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N1C)CC2=CC=CC=C2)CC(=O)O)CCCN=C(N)N
其他名称	EMD 12197,EMD-85189,EMD-121974,NSC-707544,D03497
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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