Cilnidipine
目录号: A10215
Calcium channel blocker
Cilnidipine 是一种双重阻断剂，能够阻断血管平滑肌中的 L型电压门控钙通道 和供应交感神经末梢的 N型钙通道。
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生物活性
| Discription | Cilnidipine is a dual blocker of L-type voltage-gated calcium channels in vascular smooth muscle and N-type calcium channels in sympathetic nerve terminals that supply. | |||||
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产品信息
| 目录号 | A10215 |
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| 分子式 | C27H28N2O7 |
| 分子量 | 492.52 |
| CAS号 | 132203-70-4 |
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC/C=C/C2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCOC |
| 其他名称 | FRC 8653 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 90 mg/mL (182.73 mM) | |
| Water | Insoluble | ||
| Ethanol | 14 mg/mL (28.42 mM) | ||
| In vivo | 5% DMSO+corn oil | 6 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.3 mL | 101.52 mL | 203.04 mL |
| 0.5 mM | 4.06 mL | 20.3 mL | 40.61 mL |
| 1 mM | 2.03 mL | 10.15 mL | 20.3 mL |
| 5 mM | 0.41 mL | 2.03 mL | 4.06 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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