Cilomilast (SB-207499)

目录号: A10216

PDE-4 inhibitor

Cilomilast (SB-207499) Chemical Structure

CAS NO. 153259-65-5

Cilomilast is orally active and acts as a selective Phosphodiesterase-4 inhibitor with antiinflammatory effects that target bronchoconstriction, mucus hypersecretion, and airway remodeling associated with COPD.

库存: 现货

规格 价格 数量
5 mg
¥ 750.00
10 mg
¥ 1,380.00
50 mg
¥ 4,200.00
100 mg
¥ 6,800.00
10mM * 1mL in DMSO
¥ 1,110.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Cilomilast is orally active and acts as a selective Phosphodiesterase-4 inhibitor with antiinflammatory effects that target bronchoconstriction, mucus hypersecretion, and airway remodeling associated with COPD.
靶点信息
In vitro (25°C) DMSO 69 mg/mL (200.92 mM)
Water <1 mg/mL (<1 mM)
Ethanol 50 mg/mL (145.59 mM)
In vivo 5% DMSO/95% Corn oil 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.12 mL 145.6 mL 291.21 mL
0.5 mM 5.82 mL 29.12 mL 58.24 mL
1 mM 2.91 mL 14.56 mL 29.12 mL
5 mM 0.58 mL 2.91 mL 5.82 mL

*The above data is based on the productmolecular weight 343.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10216
MECHANISM OF ACTION Inhibitor
M. Wt 343.4
Formula C20H25NO4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 153259-65-5
Synonyms SB207499, Ariflo, SB-207,499
SMILES COC1=C(C=C(C=C1)C2(CCC(CC2)C(=O)O)C#N)OC3CCCC3

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