Cilomilast (SB-207499)

Name: Cilomilast (SB-207499)
SKU: A10216
Price: 280 CNY
Rating: 5 (1 reviews)

目录号: A10216

PDE-4 抑制剂

1 篇发表文献

Cilomilast 是一种口服活性药物，作为一种选择性的磷酸二酯酶-4抑制剂，具有针对COPD相关的支气管收缩、粘液分泌过多和气道重塑的抗炎效果。

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Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥525.00	现货
25mg	¥1,085.00	现货
50mg	¥1,960.00	现货
100mg	¥2,870.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Cilomilast (SB-207499)发表的1篇文献

Esraa M Mosalam, .et al. , Int J Mol Sci, 2025, Mar 28;26(7):3108 PMID: 40243772

生物活性

Discription

Cilomilast is orally active and acts as a selective Phosphodiesterase-4 inhibitor with antiinflammatory effects that target bronchoconstriction, mucus hypersecretion, and airway remodeling associated with COPD.

Targets

Target	Value

产品信息

目录号	A10216
分子式	C20H25NO4
分子量	343.4
CAS号	153259-65-5
SMILES	COC1=C(C=C(C=C1)C2(CCC(CC2)C(=O)O)C#N)OC3CCCC3
其他名称	Ariflo
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	64 mg/mL (186.36 mM)
	Water	Insoluble
	Ethanol	47 mg/mL (136.85 mM)
In vivo	5% DMSO+95% Corn oil	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.12 mL	145.6 mL	291.21 mL
0.5 mM	5.82 mL	29.12 mL	58.24 mL
1 mM	2.91 mL	14.56 mL	29.12 mL
5 mM	0.58 mL	2.91 mL	5.82 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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