Cisapride
目录号: A21340
hERG potassium channel 抑制剂
Cisapride(R 51619) 是一种非选择性 5-HT4 受体激动剂，同时也是一种强效的 hERG 钾通道抑制剂。
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生物活性
| Discription | Cisapride(R 51619) is a nonselective 5-HT4 receptor agonist, it is also a potent hERG potassium channel inhibitor. | ||
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产品信息
| 目录号 | A21340 |
|---|---|
| 分子式 | C23H29ClFN3O4 |
| 分子量 | 465.95 |
| CAS号 | 81098-60-4 |
| SMILES | ClC1=C(N)C=C(OC)C(C(N[C@H]2[C@@H](OC)CN(CCCOC3=CC=C(F)C=C3)CC2)=O)=C1.[relative stereochemistry] |
| 其他名称 | R 51619 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 83 mg/mL (178.13 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.46 mL | 107.31 mL | 214.62 mL |
| 0.5 mM | 4.29 mL | 21.46 mL | 42.92 mL |
| 1 mM | 2.15 mL | 10.73 mL | 21.46 mL |
| 5 mM | 0.43 mL | 2.15 mL | 4.29 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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