CKD-519
目录号: A18873
CETP 抑制剂
CKD-519 是一种选择性且高效的胆固醇酯转移蛋白(CETP)抑制剂,目前正在开发中,用于治疗血脂异常症以提高高密度脂蛋白胆固醇。单剂量高达 400 毫克的 CKD-519 被良好地耐受,并显示出对 CETP 活性的强效抑制。
Discription | CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor being developed for the treatment of dyslipidemia to raise high-density lipoprotein cholesterol. Single doses of CKD-519 up to 400 mg were well tolerated and showed potent inhibition of CETP activity. |
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目录号 | A18873 |
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分子式 | C31H34F7NO3 |
分子量 | 601.6 |
CAS号 | 1402796-27-3 |
SMILES | C[C@H]1[C@@H](C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)OC(N1CC3=C(CCC(C)(C)C3)C4=C(OC)C=C(F)C(C(C)C)=C4)=O |
其他名称 | CKD-519; CKD 519; CKD519. |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2