CL-387785 (EKI-785)

Name: CL-387785 (EKI-785)
SKU: A13146
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A13146

EGFR 抑制剂

CL-387785 是一种不可逆的 EGFR 抑制剂，其 IC50 为 370+/-120 pM；能够在功能层面克服由 T790M 突变引起的抗药性。

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Grouped product items
规格	价格	库存
2mg	¥140.00	现货
5mg	¥210.00	现货
10mg	¥315.00	现货
25mg	¥700.00	现货
50mg	¥1,155.00	现货
100mg	¥1,890.00	现货
200mg	¥2,695.00	现货
*10mM 1mL in DMSO**	¥210.00	现货
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Data Sheet

SDS

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生物活性

Discription

CL-387785 is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional level.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13146
分子式	C18H13BrN4O
分子量	381.23
CAS号	194423-06-8
SMILES	CC#C/C(O)=N/C1=CC(C(NC2=CC=CC(Br)=C2)=NC=N3)=C3C=C1
其他名称	WAY-EKI 785, CL387785, CL 387785, EKI785, WAY-EKI785, EKI 785, EKI-785
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 61 mg/mL (160 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.23 mL	131.15 mL	262.31 mL
0.5 mM	5.25 mL	26.23 mL	52.46 mL
1 mM	2.62 mL	13.12 mL	26.23 mL
5 mM	0.52 mL	2.62 mL	5.25 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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