CL-387785 (EKI-785)

目录号: A13146

EGFR inhibitor

CL-387785 (EKI-785) Chemical Structure

CAS NO. 194423-06-8

CL-387785 is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional level.

库存: 现货

规格 价格 数量
10 mg
¥ 1,200.00
25 mg
¥ 2,500.00
50 mg
¥ 4,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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CL-387785 is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional level.
Targets
EGFR
370 pM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.23 mL 131.15 mL 262.31 mL
0.5 mM 5.25 mL 26.23 mL 52.46 mL
1 mM 2.62 mL 13.12 mL 26.23 mL
5 mM 0.52 mL 2.62 mL 5.25 mL

*The above data is based on the productmolecular weight 381.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13146
MECHANISM OF ACTION Inhibitor
M. Wt 381.23
Formula C18H13BrN4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 194423-06-8
Synonyms WAY-EKI 785, CL387785, CL 387785, EKI785, WAY-EKI785, EKI 785, EKI-785
SMILES CC#C/C(O)=N/C1=CC(C(NC2=CC=CC(Br)=C2)=NC=N3)=C3C=C1

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