CL2A-SN-38

目录号: A18392

DNA Topoisomerase I inhibitor

CL2A-SN-38

CL2A-SN-38 Chemical Structure

CAS NO. 1279680-68-0

CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types.

库存: 现货

规格 价格 数量
5 mg
¥ 3,500.00
10 mg
¥ 6,500.00
50 mg
¥ 20,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 6.75 mL 33.77 mL 67.54 mL
0.5 mM 1.35 mL 6.75 mL 13.51 mL
1 mM 0.68 mL 3.38 mL 6.75 mL
5 mM 0.14 mL 0.68 mL 1.35 mL

*The above data is based on the productmolecular weight 1480.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A18392
作用机制 Inhibitor (抑制剂)
M. Wt 1480.61
Formula C73H97N11O22
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1279680-68-0
SMILES O=C(O[C@](C1=C(CO2)C(N3CC4=C(CC)C5=CC(O)=CC=C5N=C4C3=C1)=O)(CC)C2=O)OCC6=CC=C(NC([C@H](CCCCN)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN7N=NC(CNC(C8CCC(CN9C(C=CC9=O)=O)CC8)=O)=C7)=O)=O)=O)C=C6

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