Cladribine

Name: Cladribine
SKU: A10223

目录号: A10223

Cladribine Chemical Structure

CAS NO. 4291-63-8

Cladribine是一种腺苷脱氨酶抑制剂，从而干扰细胞处理DNA的能力。

库存：现货

规格	价格	数量
25 mg	￥ 450.00
50 mg	￥ 700.00
100 mg	￥ 1,200.00
200 mg	￥ 2,000.00
10mM * 1mL in DMSO	￥ 640.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

Cladribine是一种腺苷脱氨酶抑制剂，从而干扰细胞处理DNA的能力。

靶点信息

Adenosine deaminase (MM1.S cells)	Adenosine deaminase (RPMI8226 cells)	Adenosine deaminase (U266 cells)
0.18 μM	0.75 μM	2.43 μM

溶解度 *

In vitro (25°C)	DMSO	52 mg/mL (182.01 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+30% PEG 300+1% Tween 80+H2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	35 mL	175.01 mL	350.02 mL
0.5 mM	7 mL	35 mL	70 mL
1 mM	3.5 mL	17.5 mL	35 mL
5 mM	0.7 mL	3.5 mL	7 mL

*The above data is based on the productmolecular weight 285.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10223
M. Wt	285.7
Formula	C10H12ClN5O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	4291-63-8
Synonyms	2-chlorodeoxyadenosine, Leustatin
SMILES	C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(N=C3N)Cl)CO)O