Clinofibrate

Name: Clinofibrate
SKU: A11184

目录号: A11184

HMG-CoA Reductase 抑制剂

Clinofibrate Chemical Structure

CAS NO. 30299-08-2

Clinofibrate是一种脂质清除剂，似乎可以改变脂质代谢，减少类固醇诱导的骨细胞内脂质堆积。它还可以有效降低血浆纤维蛋白原水平。抑制hydroxymethylglutaryl coenzyme A reductase (HMGCR)（羟甲基戊二酰辅酶A还原酶），IC50为0.47 mM。

库存：现货

规格	价格	数量
10 mg	￥ 600.00
50 mg	￥ 2,500.00
100 mg	￥ 4,500.00
10mM * 1mL in DMSO	￥ 870.00

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生物活性

靶点信息

HMGCR
0.47 mM

溶解度 *

In vitro	DMSO	90 mg/mL (192.06 mM)
	Water	Insoluble
	Ethanol	90 mg/mL (192.06 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.34 mL	106.71 mL	213.41 mL
0.5 mM	4.27 mL	21.34 mL	42.68 mL
1 mM	2.13 mL	10.67 mL	21.34 mL
5 mM	0.43 mL	2.13 mL	4.27 mL

*The above data is based on the productmolecular weight 468.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11184
作用机制	Inhibitor (抑制剂)
M. Wt	468.58
Formula	C28H36O6
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	30299-08-2
Synonyms	Lipoclin
SMILES	CCC(C(O)=O)(C)OC1=CC=C(C=C1)C2(CCCCC2)C3=CC=C(C=C3)OC(CC)(C)C(O)=O