Clomifene citrate
目录号: A10230
Clomifene 抑制下丘脑中的雌激素受体,抑制雌激素对促性腺激素释放的负反馈,从而导致下丘脑-垂体-肾上腺轴的上调。
Discription | Clomifene inhibits estrogen receptors in hypothalamus, inhibiting negative feedback of estrogen on gonadotropin release, leading to up-regulation of the hypothalamic-Cpituitary-Cadrenal axis. | ||
---|---|---|---|
Targets |
|
目录号 | A10230 |
---|---|
分子式 | C26H28ClNO.C6H8O7 |
分子量 | 598.08 |
CAS号 | 50-41-9 |
SMILES | CCN(CC)CCOC1=CC=C(C=C1)/C(=C(/C2=CC=CC=C2)\Cl)/C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 107 mg/mL (178.9 mM) | |
Water | Insoluble | ||
Ethanol | 10 mg/mL (16.72 mM) | ||
In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 2 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 16.72 mL | 83.6 mL | 167.2 mL |
0.5 mM | 3.34 mL | 16.72 mL | 33.44 mL |
1 mM | 1.67 mL | 8.36 mL | 16.72 mL |
5 mM | 0.33 mL | 1.67 mL | 3.34 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2