Clozapine

Name: Clozapine
SKU: A10236
Price: 210 CNY
Rating: 5 (6 reviews)

目录号: A10236

6 篇发表文献

氯氮平具有广泛的药理作用；其抗精神病效果主要被认为是通过5-HT2A/2C和多巴胺受体阻断来介导的。

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Grouped product items
规格	价格	库存
250mg	¥280.00	现货
500mg	¥350.00	现货
1g	¥630.00	现货
2g	¥1,050.00	现货
*10mM 1mL in DMSO**	¥210.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Clozapine发表的6篇文献

Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591

Madeleine S A Tan, .et al. , Mol Pharm, 2022, Sep 23 PMID: 36149013

Madeleine S. A. Tan, .et al. , Gels, 2022, Jan; 8(1): 38 PMID: 35049572

Milan D Valyear, .et al. , Nat Commun, 2020, Jul 28;11(1):3764 PMID: 32724058

Yutaro Kobayashi, .et al. , Transl Psychiatry, 2019, 9:181 PMID: 31371697

M.D. Valyear, .et al. , bioRxiv, 2018, 2018

生物活性

Discription

Clozapine displays a broad range of pharmacological actions; the antipsychotic effects are thought to be mediated principally by 5-HT2A/2C and dopamine receptor blockade.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10236
分子式	C18H19ClN4
分子量	326.8
CAS号	5786-21-0
SMILES	CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
其他名称	Clozaril, Fazaclo, HF 1854, Iprox, Klozapol, Leponex
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	59 mg/mL (180.52 mM)
	Water	Insoluble
	Ethanol	29 mg/mL (88.73 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.6 mL	153 mL	306 mL
0.5 mM	6.12 mL	30.6 mL	61.2 mL
1 mM	3.06 mL	15.3 mL	30.6 mL
5 mM	0.61 mL	3.06 mL	6.12 mL

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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