CM-579
目录号: A18692
G9a/DNMT 抑制剂
CM-579 是一种首创的可逆的 G9a 和 DNMT 双重抑制剂,其 IC50 值分别为 G9a 16 nM 和 DNMT 32 nM。在多种癌症细胞中具有强大的体外细胞活性。
| Discription | CM-579 is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells. | |||||
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| 目录号 | A18692 |
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| 分子式 | C29H40N4O3 |
| 分子量 | 492.65 |
| CAS号 | 1846570-40-8 |
| SMILES | CC1=CC=C(O1)C2=NC3=CC(=C(C=C3C(=C2)NCC4CCN(CC4)C)OC)OCCCN5CCCC5 |
| 其他名称 | CM579, CM 579 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2