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CNX-774

促销

BTK 抑制剂

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产品目录号: A13233

库存状态:中国现货中国现货

产品名 目录号 价格 数量
CNX-774 5mg A13233-5
¥ 1,100.00
CNX-774 10mg A13233-10
¥ 1,900.00
CNX-774 25mg A13233-25
¥ 3,600.00
CNX-774 50mg A13233-50
¥ 6,500.00
CNX-774 10mM * 1mL in DMSO A13233-10mM-D
¥ 1,350.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

CNX-774 is a potent Btk inhibitor (IC50 < 1 nM)

CNX-774

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Chemical Information

目录号 A13233
Mechanism of action Inhibitor
分子量 499.5
化学分子式 C26H22FN7O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1202759-32-7
Synonyms CNX 774; CNX774
SMILES code CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)F
化学名称 4-(4-((4-((3-acrylamidophenyl)amino)-5-fluoropyrimidin-2-yl)amino)phenoxy)-N-methylpicolinamide

生物活性

Description
CNX-774 is a potent Btk inhibitor (IC50 < 1 nM)
Targets
BTK
<1 nM

溶解性

Solubility (25°C)* In vitro DMSO 100 mg/mL (200.2 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.0 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.02 mL 100.1 mL 200.2mL
0.5 mM 4 mL 20.02 mL 40.04 mL
1 mM 2 mL 10.01 mL 20.02 mL
5 mM 0.4 mL 2 mL 4 mL

*The above data is based on the productmolecular weight 499.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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