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Cobimetinib hemifumarate

Cobimetinib hemifumarate

Name: Cobimetinib hemifumarate
SKU: A18033

目录号: A18033

MEK1 inhibitor

Cobimetinib hemifumarate Chemical Structure

CAS NO. 1369665-02-0

Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM.

库存：现货

规格	价格	数量
5 mg	￥ 1,080.00
10 mg	￥ 1,860.00
50 mg	￥ 5,520.00
100 mg	￥ 11,040.00

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生物活性

Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.45 mL	77.23 mL	154.47 mL
0.5 mM	3.09 mL	15.45 mL	30.89 mL
1 mM	1.54 mL	7.72 mL	15.45 mL
5 mM	0.31 mL	1.54 mL	3.09 mL

*The above data is based on the productmolecular weight 647.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18033
作用机制	Inhibitor (抑制剂)
M. Wt	647.38
Formula	C25H25F3IN3O6
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1369665-02-0
Synonyms	GDC-0973 hemifumarate, GDC0973, GDC 0973; XL-518 hemifumarate, XL518, XL 518
SMILES	OC1([C@H]2NCCCC2)CN(C1)C(C3=C(C(F)=C(C=C3)F)NC4=C(C=C(C=C4)I)F)=O.O=C(O)/C=C/C(O)=O.[0.5]