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Cobimetinib (racemate)

MEK 抑制剂

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产品目录号: A15050


产品名 目录号 价格 数量
Cobimetinib (racemate) 5mg A15050-5
¥ 1,400.00
Cobimetinib (racemate) 10mg A15050-10
¥ 2,100.00
Cobimetinib (racemate) 25mg A15050-25
¥ 4,200.00



Cobimetinib is a potent, highly selective inhibitor of MEK1/2.

Cobimetinib (racemate)




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Cobimetinib (racemate) 发表的文献 (1)
  • Chun-Yu Liu, .et al. Varlitinib Downregulates HER/ERK Signaling and Induces Apoptosis in Triple Negative Breast Cancer Cells, Cancers (Basel), 2019, Jan 17;11(1) PMID: 30658422

Chemical Information

目录号 A15050
Mechanism of action Inhibitor
分子量 531.31
化学分子式 C21H21F3IN3O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 934662-91-6
Synonyms GDC-0973 racemate, XL-518, GDC 0973, XL 518, GDC0973, XL518
SMILES code C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O
化学名称 [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-(3-hydroxy-3-piperidin-2-ylazetidin-1-yl)methanone


Cobimetinib is a potent, highly selective inhibitor of MEK1/2.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.82 mL 94.11 mL 188.21mL
0.5 mM 3.76 mL 18.82 mL 37.64 mL
1 mM 1.88 mL 9.41 mL 18.82 mL
5 mM 0.38 mL 1.88 mL 3.76 mL

*The above data is based on the productmolecular weight 531.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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