COH000
目录号: A17122
SUMO E1 抑制剂
COH000 是一种高度特异性的共价型异构酶 SUMO E1 抑制剂，在体外 SUMO化作用的 IC50 为 0.2 μM。
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生物活性
| Discription | COH000 is a highly specific covalent allosteric SUMO E1 inhibitor with an IC50 of 0.2 μM for SUMOylation in vitro. |
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产品信息
| 目录号 | A17122 |
|---|---|
| 分子式 | C25H25NO5 |
| 分子量 | 419.48 |
| CAS号 | 1534358-79-6 |
| SMILES | O=C(C1=C(C(OC)=O)C2C=CC1([C@H](NC3=CC=CC=C3)CC4=CC=C(C)C=C4)O2)OC |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 47 mg/mL (112.04 mM) | |
| Water | Insoluble | ||
| Ethanol | 1 mg/mL (2.38 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.84 mL | 119.2 mL | 238.39 mL |
| 0.5 mM | 4.77 mL | 23.84 mL | 47.68 mL |
| 1 mM | 2.38 mL | 11.92 mL | 23.84 mL |
| 5 mM | 0.48 mL | 2.38 mL | 4.77 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1534358-79-6 | 1534358-79-6 供应商 | 1534358-79-6 花费 | 1534358-79-6 生产商 | 订购 1534358-79-6 | 1534358-79-6 代理商