Compound 401

目录号: A11778

DNA-PK inhibitor

Compound 401 Chemical Structure

CAS NO. 168425-64-7

Compound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over mTOR (IC50 = 5.3 μM).

库存: 现货

规格 价格 数量
10 mg
¥ 1,250.00
25 mg
¥ 3,000.00
50 mg
¥ 4,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Compound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over mTOR (IC50 = 5.3 μM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.55 mL 177.74 mL 355.48 mL
0.5 mM 7.11 mL 35.55 mL 71.1 mL
1 mM 3.55 mL 17.77 mL 35.55 mL
5 mM 0.71 mL 3.55 mL 7.11 mL

*The above data is based on the productmolecular weight 281.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11778
MECHANISM OF ACTION Inhibitor
M. Wt 281.31
Formula C16H15N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 168425-64-7
Synonyms N/A
SMILES C1COCCN1C2=CC(=O)N3C=CC4=CC=CC=C4C3=N2

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