Signaling Pathway
Conatumumab (AMG 655) is a human monoclonal agonist antibody targeting human death receptor 5 (DR5, TRAILR2), displaying high affinity with dissociation constants (Kd) of 1 nM for the long form of DR5 and 0.8 nM for the short form. This antibody functions by inducing apoptosis through caspase activation, making it highly relevant for cancer research applications.
重要通知：仅供研究使用。我们不向患者销售。
| Discription | Conatumumab (AMG 655) is a human monoclonal agonist antibody targeting human death receptor 5 (DR5, TRAILR2), displaying high affinity with dissociation constants (Kd) of 1 nM for the long form of DR5 and 0.8 nM for the short form. This antibody functions by inducing apoptosis through caspase activation, making it highly relevant for cancer research applications. |
||
|---|---|---|---|
| Targets |
|
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
