Costunolide
目录号: A10240
Telomerase 抑制剂
Costunolide 是一种抑制人类端粒酶活性的抑制剂（在 MCF-7 乳腺癌细胞中的 IC50 为 65 μM）。它被描述为具有抗氧化、抗结核、抗炎和抗病毒作用，并具有细胞毒性活性。
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生物活性
| Discription | Costunolide is an Inhibitor of human telomerase activity (IC50 = 65 μM in MCF-7 breast cancer cells). It is described to act as an antioxidant, anti-mycobacterial, anti-inflammatory, and anti-viral, with cytotoxic activity. | |||||
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产品信息
| 目录号 | A10240 |
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| 分子式 | C15H20O2 |
| 分子量 | 232.3 |
| CAS号 | 553-21-9 |
| SMILES | CC1=CCC/C(=C/[C@@H]2[C@@H](CC1)C(=C)C(=O)O2)/C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 43 mg/mL (185.08 mM) | |
| Water | Insoluble | ||
| Ethanol | 1 mg/mL (4.3 mM) | ||
| In vivo | 2% DMSO+corn oil | 9 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 43.05 mL | 215.24 mL | 430.48 mL |
| 0.5 mM | 8.61 mL | 43.05 mL | 86.1 mL |
| 1 mM | 4.3 mL | 21.52 mL | 43.05 mL |
| 5 mM | 0.86 mL | 4.3 mL | 8.61 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 553-21-9 | 553-21-9 供应商 | 553-21-9 花费 | 553-21-9 生产商 | 订购 553-21-9 | 553-21-9 代理商