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CP 31398 dihydrochloride是p53稳定剂。在具有突变型或野生型p53的癌细胞系中稳定p53的活性构象并提高p53的活性。在体内抑制小的人类肿瘤异种移植物的生长。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.97 mL | 114.84 mL | 229.68 mL |
| 0.5 mM | 4.59 mL | 22.97 mL | 45.94 mL |
| 1 mM | 2.3 mL | 11.48 mL | 22.97 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.59 mL |
*The above data is based on the productmolecular weight 435.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15346 |
|---|---|
| 作用机制 | Stabilizer (稳定剂) |
| M. Wt | 435.39 |
| Formula | C22H26N4O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1217195-61-3 |
| SMILES | Cl.Cl.O(C3=CC=C(C=CC2=NC1=CC=CC=C1C(=N2)NCCCN(C)C)C=C3)C |
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