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CP-465022 hydrochloride

目录号: A67214
AMPA Receptor Antagonist
CP-465022 hydrochloride is a selective noncompetitive antagonist of the AMPA receptor, exhibiting significant anticonvulsant activity. It effectively inhibits kainate-induced responses in rat cortical neurons with an IC50 of 25 nM. This compound serves as a valuable tool for exploring the physiological and pathophysiological roles of AMPA receptors in various neurological contexts.
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Discription CP-465022 hydrochloride is a selective noncompetitive antagonist of the AMPA receptor, exhibiting significant anticonvulsant activity. It effectively inhibits kainate-induced responses in rat cortical neurons with an IC50 of 25 nM. This compound serves as a valuable tool for exploring the physiological and pathophysiological roles of AMPA receptors in various neurological contexts.
产品信息
目录号 A67214
分子式 C26H25Cl2FN4O
分子量 499.41
CAS号 1785666-59-2
SMILES O=C1N(C2=CC=CC=C2Cl)C(/C=C/C3=NC(CN(CC)CC)=CC=C3)=NC4=C1C=C(F)C=C4.[H]Cl
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