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CP-640186 hydrochloride is a potent and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.15 mL | 95.77 mL | 191.54 mL |
| 0.5 mM | 3.83 mL | 19.15 mL | 38.31 mL |
| 1 mM | 1.92 mL | 9.58 mL | 19.15 mL |
| 5 mM | 0.38 mL | 1.92 mL | 3.83 mL |
*The above data is based on the productmolecular weight 522.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21808 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 522.08 |
| Formula | C30H36ClN3O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 591778-70-0 |
| Synonyms | CP 640186, CP640186 |
| SMILES | O=C([C@H]1CN(C2CCN(C(C3=C(C=CC=C4)C4=CC5=C3C=CC=C5)=O)CC2)CCC1)N6CCOCC6.Cl |
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