CP-673451

目录号: A11350

PDGFRα/β inhibitor

CP-673451 Chemical Structure

CAS NO. 343787-29-1

CP 673451 is a potent PDGFR-β inhibitor with an IC50 of 1 nM.

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 2,000.00
25 mg
¥ 3,800.00
50 mg
¥ 6,800.00
10mM * 1mL in DMSO
¥ 1,590.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

CP 673451 is a potent PDGFR-β inhibitor with an IC50 of 1 nM.
Targets
Target Value
PDGFRβIC50: 1nM
PDGFRαIC50: 10nM
c-KitIC50: 252nM
VEGFR1IC50: 450nM
VEGFR2IC50: 450nM
LCKIC50: >1μM
SrcIC50: >2μM
v-AblIC50: >5μM
Tie-2IC50: >5μM
bFGFRIC50: >5μM
EGFRIC50: >10μM
ErbB2IC50: >10μM
c-MetIC50: >10μM
IGF-1RIC50: >10μM
In vitro DMSO 28 mg/mL heating (67.06 mM)
Water <1 mg/mL (<1 mM)
Ethanol 4 mg/mL (9.58 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.95 mL 119.76 mL 239.52 mL
0.5 mM 4.79 mL 23.95 mL 47.9 mL
1 mM 2.4 mL 11.98 mL 23.95 mL
5 mM 0.48 mL 2.4 mL 4.79 mL

*The above data is based on the productmolecular weight 417.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11350
MECHANISM OF ACTION Inhibitor
M. Wt 417.5
Formula C24H27N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 343787-29-1
Synonyms CP673451
SMILES COCCOC1=CC2=C(C=C1)N(C=N2)C3=NC4=C(C=CC=C4N5CCC(CC5)N)C=C3

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