CP-724714

目录号: A10242

HER2/ErbB2 inhibitor

CP-724714

CP-724714 Chemical Structure

CAS NO. 537705-08-1

CP-724714 is an orally available, small molecule, potent HER-2 tyrosine kinase inhibitor that inhibits HER2 kinase (IC50 3.8 ng/ml) .

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 1,000.00
25 mg
¥ 2,300.00
50 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 1,150.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

CP-724714 is an orally available, small molecule, potent HER-2 tyrosine kinase inhibitor that inhibits HER2 kinase (IC50 3.8 ng/ml) .
Targets
HER2/ErbB2 (Cell-free assay)
10 nM
In vitro (25°C) DMSO 94 mg/mL (200.2 mM)
Water <1 mg/mL (<1 mM)
Ethanol 94 mg/mL (200.2 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.3 mL 106.5 mL 212.99 mL
0.5 mM 4.26 mL 21.3 mL 42.6 mL
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL

*The above data is based on the productmolecular weight 469.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10242
MECHANISM OF ACTION Inhibitor
M. Wt 469.5
Formula C27H27N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 537705-08-1
Synonyms CP724714
SMILES CC1=NC=C(C=C1)OC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)C=CCNC(=O)COC)C

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