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CP 945598 HCl (Otenabant HCl)

CB1 拮抗剂

158 Customer Reviews
产品目录号: A11942

库存状态:中国现货中国现货

产品名 目录号 价格 数量
CP 945598 hydrochloride 10mg A11942-10
¥ 1,000.00
CP 945598 hydrochloride 25mg A11942-25
¥ 1,500.00
CP 945598 hydrochloride 50mg A11942-50
¥ 3,500.00
CP 945598 hydrochloride 100mg A11942-100
¥ 4,800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

CP 945598 is a potent and highly selective CB1 antagonist.

CP 945598 HCl (Otenabant HCl)

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Chemical Information

目录号 A11942
Mechanism of action Antagonist
分子量 546.9
化学分子式 C25H25Cl2N7O.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 686347-12-6
Synonyms CP-945598, Otenabant, CP-945,598
SMILES code CCNC1(CCN(CC1)C2=NC=NC3=C2N=C(N3C4=CC=C(C=C4)Cl)C5=CC=CC=C5Cl)C(=O)N.Cl
化学名称 1-[8-(2-Chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)piperidine-4-carboxamide hydrochloride

生物活性

Description
CP 945598 is a potent and highly selective CB1 antagonist.
Targets
hCB1 rCB1 hCB2
0.7 nM(Ki)2.8 nM(Ki)7.663 μM(Ki)

溶解性

Solubility (25°C) * In vitro DMSO 1 mg/mL heating (1.82 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 17 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.28 mL 91.42 mL 182.85mL
0.5 mM 3.66 mL 18.28 mL 36.57 mL
1 mM 1.83 mL 9.14 mL 18.28 mL
5 mM 0.37 mL 1.83 mL 3.66 mL

*The above data is based on the productmolecular weight 546.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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