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Lirametostat (CPI-1205)

目录号: A16357
EZH2 抑制剂
Lirametostat(CPI-1205)是一种高效(生化 IC50 = 0.002 μM,细胞 EC50 = 0.032 μM)且选择性的 EZH2 抑制剂。
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规格 价格 库存 数量
1mg
¥560.00
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2mg
¥595.00
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5mg
¥1,225.00
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10mg
¥2,205.00
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25mg
¥3,850.00
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50mg
¥5,425.00
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10mM * 1mL in DMSO
¥3,255.00
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Lirametostat (CPI-1205)发表的1篇文献
  • George L.Joun, .et al. , bioRxiv, 2025, Jan 8
  • 生物活性
    Discription

    Lirametostat (CPI-1205) is a highly potent (biochemical IC50 = 0.002 μM, cellular EC50 = 0.032 μM) and selective inhibitor of EZH2.

    产品信息
    目录号 A16357
    分子式 C27H33F3N4O3
    分子量 518.57
    CAS号 1621862-70-1
    SMILES CC1=CC(OC)=C(CNC(C2=C(C)N([C@H](C)C3CCN(CC(F)(F)F)CC3)C4=C2C=CC=C4)=O)C(N1)=O
    其他名称 CPI 1205, CPI1205
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 90 mg/mL (173.55 mM)
    Water Insoluble
    Ethanol 90 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.28 mL 96.42 mL 192.84 mL
    0.5 mM 3.86 mL 19.28 mL 38.57 mL
    1 mM 1.93 mL 9.64 mL 19.28 mL
    5 mM 0.39 mL 1.93 mL 3.86 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

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