Lirametostat(CPI-1205)是一种高效(生化 IC50 = 0.002 μM,细胞 EC50 = 0.032 μM)且选择性的 EZH2 抑制剂。
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Adooq用户使用Lirametostat (CPI-1205)发表的1篇文献
生物活性
| Discription | Lirametostat (CPI-1205) is a highly potent (biochemical IC50 = 0.002 μM, cellular EC50 = 0.032 μM) and selective inhibitor of EZH2. |
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产品信息
| 目录号 | A16357 |
|---|---|
| 分子式 | C27H33F3N4O3 |
| 分子量 | 518.57 |
| CAS号 | 1621862-70-1 |
| SMILES | CC1=CC(OC)=C(CNC(C2=C(C)N([C@H](C)C3CCN(CC(F)(F)F)CC3)C4=C2C=CC=C4)=O)C(N1)=O |
| 其他名称 | CPI 1205, CPI1205 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 90 mg/mL (173.55 mM) | |
| Water | Insoluble | ||
| Ethanol | 90 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.28 mL | 96.42 mL | 192.84 mL |
| 0.5 mM | 3.86 mL | 19.28 mL | 38.57 mL |
| 1 mM | 1.93 mL | 9.64 mL | 19.28 mL |
| 5 mM | 0.39 mL | 1.93 mL | 3.86 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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