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EZH2 抑制剂

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产品目录号: A16357


产品名 目录号 价格 数量
CPI-1205 2mg A16357-2
¥ 900.00
CPI-1205 5mg A16357-5
¥ 1,800.00
CPI-1205 10mg A16357-10
¥ 3,200.00



CPI-1205 is a highly potent (biochemical IC50 = 0.002 μM, cellular EC50 = 0.032 μM) and selective inhibitor of EZH2.





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Chemical Information

目录号 A16357
Mechanism of action Inhibitor
分子量 518.57
化学分子式 C27H33F3N4O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1621862-70-1
Synonyms CPI 1205, CPI1205
SMILES code CC1=CC(OC)=C(CNC(C2=C(C)N([C@H](C)C3CCN(CC(F)(F)F)CC3)C4=C2C=CC=C4)=O)C(N1)=O
化学名称 (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide


CPI-1205 is a highly potent (biochemical IC50 = 0.002 μM, cellular EC50 = 0.032 μM) and selective inhibitor of EZH2.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.28 mL 96.42 mL 192.84mL
0.5 mM 3.86 mL 19.28 mL 38.57 mL
1 mM 1.93 mL 9.64 mL 19.28 mL
5 mM 0.39 mL 1.93 mL 3.86 mL

*The above data is based on the productmolecular weight 518.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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