CPI-169

目录号: A15920

EZH2 inhibitor

CPI-169

CPI-169 Chemical Structure

CAS NO. 1450655-76-1

CPI-169 is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 1,800.00
25 mg
¥ 4,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

CPI-169 is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.
Targets
EZH2 WT EZH2 Y641N EZH1
0.24 nM0.51 nM6.1 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.92 mL 94.58 mL 189.16 mL
0.5 mM 3.78 mL 18.92 mL 37.83 mL
1 mM 1.89 mL 9.46 mL 18.92 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 528.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A15920
MECHANISM OF ACTION Inhibitor
M. Wt 528.66
Formula C27H36N4O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1450655-76-1
Synonyms CPI 169, CPI169
SMILES CCS(N1CCC([C@@](N2C(C)=C(/C(O)=N/CC(C(O)=N3)=C(OC)C=C3C)C4=CC=CC=C42)([H])C)CC1)(=O)=O

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