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CPI-268456

目录号: A15828
CPI-268456 是溴结构域蛋白 4(BRD4)的配体。它与 BRD4 结合(在无细胞测定中 IC50 = <0.5 μM)并抑制 THP-1 细胞中 LPS 诱导的 IL-6 分泌(IC50 = <0.5 μM)。
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规格 价格 库存 数量
1mg
¥455.00
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5mg
¥945.00
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10mg
¥1,715.00
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25mg
¥3,815.00
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生物活性
Discription CPI-268456 is a ligand of bromodomain-containing protein 4 (BRD4). It binds to BRD4 (IC50 = <0.5 μM in a cell-free assay) and inhibits LPS-induced IL-6 secretion in THP-1 cells (IC50 = <0.5 μM).
产品信息
目录号 A15828
分子式 C20H15Cl2N3O2
分子量 399.05
CAS号 1380087-86-4
SMILES C(N)(=O)C[C@@H]1N=C(C2=CC=C(Cl)C=C2)C2=CC(Cl)=CC=C2C2C(C)=NOC=21
其他名称 CPI 268456, CPI268456
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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