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EZH1 抑制剂

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产品目录号: A15908


产品名 目录号 价格 数量
CPI-360 5mg A15908-5
¥ 1,400.00
CPI-360 10mg A15908-10
¥ 1,950.00
CPI-360 25mg A15908-25
¥ 4,200.00



CPI-360 is a potent, selective,and SAM-competitive EZH1 inhibitor with IC50 of 102.3 nM, >100-fold selectivity over other methyltransferases.





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Chemical Information

目录号 A15908
Mechanism of action Inhibitor
分子量 437.53
化学分子式 C25H31N3O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1802175-06-9
Synonyms CPI360, CPI 360
SMILES code CC(N1)=CC(OC)=C(CNC(C2=C(C)N([C@H](C)C3CCOCC3)C4=C2C=CC=C4)=O)C1=O
化学名称 (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(tetrahydro-2H-pyran-4-yl)ethyl)-1H-indole-3-carboxamide


CPI-360 is a potent, selective,and SAM-competitive EZH1 inhibitor with IC50 of 102.3 nM, >100-fold selectivity over other methyltransferases.
102.3 nM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.86 mL 114.28 mL 228.56mL
0.5 mM 4.57 mL 22.86 mL 45.71 mL
1 mM 2.29 mL 11.43 mL 22.86 mL
5 mM 0.46 mL 2.29 mL 4.57 mL

*The above data is based on the productmolecular weight 437.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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