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CPI 4203

KDM5 demethylases 抑制剂

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产品目录号: A16177

库存状态:中国现货中国现货

产品名 目录号 价格 数量
CPI 4203 5mg A16177-5
¥ 900.00
CPI 4203 10mg A16177-10
¥ 1,600.00
CPI 4203 50mg A16177-50
¥ 6,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

CPI 4203 is a selective inhibitor of KDM5 demethylases, structurally related to CPI 455 but ~25-fold less potent (IC50 value 250 nM for inhibition of full length KDM5A).

CPI 4203

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Chemical Information

目录号 A16177
Mechanism of action Inhibitor
分子量 278.32
化学分子式 C16H14N4O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1628214-07-2
Synonyms CPI-4203, CPI4203
SMILES code CCC1=C(N=C2C(=CNN2C1=O)C#N)C3=CC=CC=C3C
化学名称 6-ethyl-5-(2-methylphenyl)-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile

生物活性

Description
CPI 4203 is a selective inhibitor of KDM5 demethylases, structurally related to CPI 455 but ~25-fold less potent (IC50 value 250 nM for inhibition of full length KDM5A).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.93 mL 179.65 mL 359.3mL
0.5 mM 7.19 mL 35.93 mL 71.86 mL
1 mM 3.59 mL 17.96 mL 35.93 mL
5 mM 0.72 mL 3.59 mL 7.19 mL

*The above data is based on the productmolecular weight 278.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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