Crizanlizumab is a monoclonal antibody that targets P-selectin, effectively inhibiting its interaction with P-selectin glycoprotein ligand 1 (PSGL-1). By blocking this interaction, Crizanlizumab plays a crucial role in preventing vaso-occlusive crises (VOCs), making it a valuable tool for the study and research of sickle cell disease pathophysiology and therapeutic interventions.
Crizanlizumab is a monoclonal antibody that targets P-selectin, effectively inhibiting its interaction with P-selectin glycoprotein ligand 1 (PSGL-1). By blocking this interaction, Crizanlizumab plays a crucial role in preventing vaso-occlusive crises (VOCs), making it a valuable tool for the study and research of sickle cell disease pathophysiology and therapeutic interventions.
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