CTEP

目录号: A11968

CTEP

CTEP Chemical Structure

CAS NO. 871362-31-1

CTEP is a highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor with an IC50 of 2.2 nM.

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,800.00
50 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

CTEP is a highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor with an IC50 of 2.2 nM.
Targets
mGlu5
2.2 nM
In vitro (25°C) DMSO 78 mg/mL (199.09 mM)
Water <1 mg/mL (<1 mM)
Ethanol 10 mg/mL (25.52 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 6 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.53 mL 127.63 mL 255.25 mL
0.5 mM 5.11 mL 25.53 mL 51.05 mL
1 mM 2.55 mL 12.76 mL 25.53 mL
5 mM 0.51 mL 2.55 mL 5.11 mL

*The above data is based on the productmolecular weight 391.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11968
MECHANISM OF ACTION N/A
M. Wt 391.77
Formula C19H13ClF3N3O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 871362-31-1
Synonyms N/A
SMILES CC1=C(N=C(N1C2=CC=C(C=C2)OC(F)(F)F)C)C#CC3=CC(=NC=C3)Cl

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