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HDAC 抑制剂

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产品目录号: A10246


产品名 目录号 价格 数量
CUDC-101 10mg A10246-10
¥ 700.00
CUDC-101 50mg A10246-50
¥ 2,600.00
CUDC-101 100mg A10246-100
¥ 4,800.00
CUDC-101 200mg A10246-200
¥ 7,200.00
CUDC-101 10mM * 1mL in DMSO A10246-10mM-D
¥ 890.00



CUDC-101 is a novel compound which inhibits multiple targets, which is designed to inhibit HDAC, EGFR and Her2.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A10246
Mechanism of action Inhibitor
分子量 434.5
化学分子式 C24H26N4O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1012054-59-9
Synonyms CUDC101
化学名称 7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide


CUDC-101 is a novel compound which inhibits multiple targets, which is designed to inhibit HDAC, EGFR and Her2.
Target Value
EGFRIC50: 2.4nM
HDACIC50: 4.4nM
HDAC1IC50: 4.5nM
HDAC6IC50: 5.1nM
HDAC3IC50: 9.1nM
HDAC5IC50: 11.4nM
HDAC2IC50: 12.6nM
HDAC4IC50: 13.2nM
HER2IC50: 15.7nM
HDAC10IC50: 26.1nM
HDAC9IC50: 67.2nM
HDAC8IC50: 79.8nM
HDAC7IC50: 373nM


Solubility (25°C) * In vitro DMSO 20 mg/mL (46.03 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.01 mL 115.07 mL 230.15mL
0.5 mM 4.6 mL 23.01 mL 46.03 mL
1 mM 2.3 mL 11.51 mL 23.01 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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