CUDC-101

目录号: A10246

HDAC 抑制剂

CUDC-101

CUDC-101 Chemical Structure

CAS NO. 1012054-59-9

CUDC-101是一种抑制多种靶标的新型化合物,旨在抑制HDAC,EGFR和Her2。

库存: 现货

规格 价格 数量
10 mg
¥ 700.00
50 mg
¥ 2,600.00
100 mg
¥ 4,800.00
200 mg
¥ 7,200.00
10mM * 1mL in DMSO
¥ 890.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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CUDC-101是一种抑制多种靶标的新型化合物,旨在抑制HDAC,EGFR和Her2。
Targets
Target Value
EGFRIC50: 2.4nM
HDACIC50: 4.4nM
HDAC1IC50: 4.5nM
HDAC6IC50: 5.1nM
HDAC3IC50: 9.1nM
HDAC5IC50: 11.4nM
HDAC2IC50: 12.6nM
HDAC4IC50: 13.2nM
HER2IC50: 15.7nM
HDAC10IC50: 26.1nM
HDAC9IC50: 67.2nM
HDAC8IC50: 79.8nM
HDAC7IC50: 373nM
In vitro (25°C) DMSO 20 mg/mL (46.03 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 15% Captisol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.01 mL 115.07 mL 230.15 mL
0.5 mM 4.6 mL 23.01 mL 46.03 mL
1 mM 2.3 mL 11.51 mL 23.01 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10246
作用机制 Inhibitor (抑制剂)
M. Wt 434.5
Formula C24H26N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1012054-59-9
Synonyms CUDC101
SMILES COC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCCCCCC(=O)NO

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