CUDC-305 (DEBIO-0932 )

目录号: A12648

HSP90 inhibitor

CUDC-305 (DEBIO-0932 ) Chemical Structure

CAS NO. 1061318-81-7

Debio 0932 is a novel heat shock protein 90 (HSP90) inhibitor with strong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L), including many non-small cell lung cancer (NSCLC) cell lines which are resistant to standard-of-care (SOC) agents.

库存: 现货

规格 价格 数量
5 mg
¥ 1,100.00
10 mg
¥ 1,700.00
25 mg
¥ 3,500.00
50 mg
¥ 5,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Debio 0932 is a novel heat shock protein 90 (HSP90) inhibitor with strong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L), including many non-small cell lung cancer (NSCLC) cell lines which are resistant to standard-of-care (SOC) agents.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.59 mL 112.97 mL 225.95 mL
0.5 mM 4.52 mL 22.59 mL 45.19 mL
1 mM 2.26 mL 11.3 mL 22.59 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12648
MECHANISM OF ACTION Inhibitor
M. Wt 442.58
Formula C22H30N6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1061318-81-7
Synonyms Debio0932; CUDC305
SMILES CC(C)(C)CNCCN1C2=C(C(=NC=C2)N)N=C1SC3=CC4=C(C=C3N(C)C)OCO4

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