CUDC-907 (Fimepinostat)

目录号: A11153

PI3K/HDAC 抑制剂

CUDC-907 (Fimepinostat)

CUDC-907 (Fimepinostat) Chemical Structure

CAS NO. 1339928-25-4

CUDC-907 (Fimepinostat)是针对PI3K和HDAC的单一小分子抑制剂,作用于PI3Kα和HDAC1/2/3/10,IC50分别为19 nM和1.7 nM/5 nM/1.8 nM/2.8 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 1,250.00
10 mg
¥ 1,750.00
50 mg
¥ 4,700.00
100 mg
¥ 9,000.00
10mM * 1mL in DMSO
¥ 1,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

CUDC-907 (Fimepinostat)是针对PI3K和HDAC的单一小分子抑制剂,作用于PI3Kα和HDAC1/2/3/10,IC50分别为19 nM和1.7 nM/5 nM/1.8 nM/2.8 nM。
Targets
Target Value
HDAC1IC50: 1.7nM
HDAC3IC50: 1.8nM
HDAC10IC50: 2.8nM
HDAC2IC50: 5.0nM
HDAC11IC50: 5.4nM
PI3KαIC50: 19nM
HDAC6IC50: 27nM
PI3KδIC50: 39nM
PI3KβIC50: 54nM
HDAC8IC50: 191nM
PI3KγIC50: 311nM
HDAC4IC50: 409nM
HDAC7IC50: 426nM
HDAC9IC50: 554nM
HDAC5IC50: 674nM
In vitro DMSO 102 mg/mL (200.57 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.66 mL 98.31 mL 196.62 mL
0.5 mM 3.93 mL 19.66 mL 39.32 mL
1 mM 1.97 mL 9.83 mL 19.66 mL
5 mM 0.39 mL 1.97 mL 3.93 mL

*The above data is based on the productmolecular weight 508.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11153
作用机制 Inhibitor (抑制剂)
M. Wt 508.6
Formula C23H24N8O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1339928-25-4
Synonyms CUDC907
SMILES CN(CC1=CC2=C(S1)C(=NC(=N2)C3=CN=C(C=C3)OC)N4CCOCC4)C5=NC=C(C=N5)C(=O)NO

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 CUDC-907 (Fimepinostat) | CUDC-907 (Fimepinostat) 供应商 | 订购 CUDC-907 (Fimepinostat) | CUDC-907 (Fimepinostat) 价格 | CUDC-907 (Fimepinostat) 生产商 | 订单 CUDC-907 (Fimepinostat) | CUDC-907 (Fimepinostat) 代理商 | 购买 1339928-25-4| 1339928-25-4 供应商 | 订购 1339928-25-4 | 1339928-25-4 价格 | 1339928-25-4 生产商 | 订单 1339928-25-4 | 1339928-25-4 代理商|buy CUDC-907 (Fimepinostat) | CUDC-907 (Fimepinostat) Supplier | purchase CUDC-907 (Fimepinostat) | CUDC-907 (Fimepinostat) cost | CUDC-907 (Fimepinostat) manufacturer | order CUDC-907 (Fimepinostat) | CUDC-907 (Fimepinostat) distributor | buy 1339928-25-4| 1339928-25-4 Supplier | purchase 1339928-25-4 | 1339928-25-4 cost | 1339928-25-4 manufacturer | order 1339928-25-4 | 1339928-25-4 distributor
Rewards