Cusatuzumab (ARGX-110) is a humanized monoclonal antibody targeting CD70. It exhibits enhanced antibody-dependent cellular cytotoxicity (ADCC) and effectively blocks the CD70/CD27 signaling pathway. By inhibiting this pathway, cusatuzumab reduces the population of leukemia stem cells (LSCs) and induces gene signatures associated with myeloid differentiation and apoptosis. This antibody is particularly useful in research focused on the pathophysiology and potential therapeutic interventions for leukemia.
Cusatuzumab (ARGX-110) is a humanized monoclonal antibody targeting CD70. It exhibits enhanced antibody-dependent cellular cytotoxicity (ADCC) and effectively blocks the CD70/CD27 signaling pathway. By inhibiting this pathway, cusatuzumab reduces the population of leukemia stem cells (LSCs) and induces gene signatures associated with myeloid differentiation and apoptosis. This antibody is particularly useful in research focused on the pathophysiology and potential therapeutic interventions for leukemia.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
