CVT-313
目录号: A15054
CDK2 抑制剂
CVT-313 是一种强效、选择性、可逆的、与ATP竞争的 CDK2 抑制剂(对 Cdk2/A 和 Cdk2/E 的 IC50 为 0.5 uM;对 Cdk1/B 的 IC50 为 4.2 uM;对 Cdk4/D1 的 IC50 为 215 uM)。
Discription | CVT-313 is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2 (IC50 = 0.5 uM for Cdk2/A and Cdk2/E; 4.2 uM for Cdk1/B; 215 uM for Cdk4/D1). | |||||
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Targets |
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Cell Research |
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目录号 | A15054 |
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分子式 | C20H28N6O3 |
分子量 | 400.47 |
CAS号 | 199986-75-9 |
SMILES | CC(C)N1C=NC2=C1N=C(N=C2NCC3=CC=C(C=C3)OC)N(CCO)CCO |
其他名称 | CVT 313, NG 26, CVT313, NG26, NG-26 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 73 mg/mL (182.28 mM) | |
Water | Insoluble | ||
Ethanol | 73 mg/mL (182.28 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.97 mL | 124.85 mL | 249.71 mL |
0.5 mM | 4.99 mL | 24.97 mL | 49.94 mL |
1 mM | 2.5 mL | 12.49 mL | 24.97 mL |
5 mM | 0.5 mL | 2.5 mL | 4.99 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2