CX-6258 HCl

目录号: A14275

Pan-PIM kinase inhibitor

CX-6258 HCl

CX-6258 HCl Chemical Structure

CAS NO. 1353859-00-3

CX-6258 HCl is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3.

库存: 现货

规格 价格 数量
5 mg
¥ 1,100.00
10 mg
¥ 1,800.00
25 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 1,690.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

CX-6258 HCl is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3.
Targets
Pim1 Pim3 Pim2
5 nM16 nM25 nM
In vitro DMSO 57 mg/mL heating (114.36 mM)
Water 89 mg/mL heating (178.57 mM)
Ethanol 1 mg/mL heating (2.0 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.06 mL 100.32 mL 200.64 mL
0.5 mM 4.01 mL 20.06 mL 40.13 mL
1 mM 2.01 mL 10.03 mL 20.06 mL
5 mM 0.4 mL 2.01 mL 4.01 mL

*The above data is based on the productmolecular weight 498.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A14275
MECHANISM OF ACTION Inhibitor
M. Wt 498.4
Formula C26H24ClN3O3.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1353859-00-3
Synonyms CX6258
SMILES CN1CCCN(CC1)C(=O)C2=CC=CC(=C2)C3=CC=C(O3)/C=C/4\C5=C(C=CC(=C5)Cl)NC4=O.Cl

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