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CX-6258 HCl

Pan-PIM kinase 抑制剂

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产品目录号: A14275


产品名 目录号 价格 数量
CX-6258 HCl 5mg A14275-5
¥ 1,100.00
CX-6258 HCl 10mg A14275-10
¥ 1,800.00
CX-6258 HCl 25mg A14275-25
¥ 4,000.00
CX-6258 HCl 10mM * 1mL in DMSO A14275-10mM-D
¥ 1,690.00



CX-6258 HCl is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3.

CX-6258 HCl




顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A14275
Mechanism of action Inhibitor
分子量 498.4
化学分子式 C26H24ClN3O3.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1353859-00-3
Synonyms CX6258
SMILES code CN1CCCN(CC1)C(=O)C2=CC=CC(=C2)C3=CC=C(O3)/C=C/4\C5=C(C=CC(=C5)Cl)NC4=O.Cl
化学名称 (3E)-5-chloro-3-[[5-[3-[(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)carbonyl]phenyl]-2-furanyl]methylene]-1,3-dihydro-2H-Indol-2-one, hydrochloride (1:1)


CX-6258 HCl is a potent, orally efficacious pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3.
Pim1 Pim3 Pim2
5 nM16 nM25 nM


Solubility (25°C)* In vitro DMSO 57 mg/mL heating (114.36 mM)
Water 89 mg/mL heating (178.57 mM)
Ethanol 1 mg/mL heating (2.0 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.06 mL 100.32 mL 200.64mL
0.5 mM 4.01 mL 20.06 mL 40.13 mL
1 mM 2.01 mL 10.03 mL 20.06 mL
5 mM 0.4 mL 2.01 mL 4.01 mL

*The above data is based on the productmolecular weight 498.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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