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Cycloheximide (Actidione)用作选择性抗生素。它抑制腐菌真菌真核生物的蛋白质合成(DNA依赖性RNA)。通过与80S核糖体结合而对皮肤真菌和系统性真菌无效。
| In vitro | DMSO | 48 mg/mL (170.61 mM) | |
| Water | 13 mg/mL (46.2 mM) | ||
| Ethanol | 48 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.54 mL | 177.68 mL | 355.37 mL |
| 0.5 mM | 7.11 mL | 35.54 mL | 71.07 mL |
| 1 mM | 3.55 mL | 17.77 mL | 35.54 mL |
| 5 mM | 0.71 mL | 3.55 mL | 7.11 mL |
*The above data is based on the productmolecular weight 281.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10036 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 281.4 |
| Formula | C15H23NO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 66-81-9 |
| SMILES | C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C |
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