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Hedgehog signaling 抑制剂

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产品目录号: A10249


产品名 目录号 价格 数量
Cyclopamine 5mg A10249-5
¥ 450.00
Cyclopamine 10mg A10249-10
¥ 800.00
Cyclopamine 25mg A10249-25
¥ 1,600.00
Cyclopamine 50mg A10249-50
¥ 3,000.00



Cyclopamine is a Smo or hedgehog signaling pathway inhibitor.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A10249
Mechanism of action Inhibitor
分子量 411.6
化学分子式 C27H41NO2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 4449-51-8
Synonyms 11-deoxojervine
SMILES code C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5CC4=C3C)C)O)C)NC1
化学名称 (3β,23R)-17,23-Epoxyveratraman-3-ol


Cyclopamine is a Smo or hedgehog signaling pathway inhibitor.
Smoothened (TM3Hh12 cells)
46 nM


Solubility (25°C)* In vitro DMSO <1 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol 4 mg/mL heating (9.71 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.3 mL 121.48 mL 242.95mL
0.5 mM 4.86 mL 24.3 mL 48.59 mL
1 mM 2.43 mL 12.15 mL 24.3 mL
5 mM 0.49 mL 2.43 mL 4.86 mL

*The above data is based on the productmolecular weight 411.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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