Cyclosporine
目录号: A15434
Calcineurin 抑制剂
环孢素是一种钙调磷酸酶通路抑制剂,用作免疫抑制药物,以防止器官移植后的排斥反应。
| Discription | Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. | ||
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| 目录号 | A15434 |
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| 分子式 | C62H111N11O12 |
| 分子量 | 1202.61 |
| CAS号 | 79217-60-0 |
| SMILES | CCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | Warmed: 85 mg/mL (70.68 mM) | |
| Water | Insoluble | ||
| Ethanol | 85 mg/mL (70.68 mM) | ||
| In vivo | 2% DMSO+40% PEG 300+2% Tween 80+ddH2O | 2 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 8.32 mL | 41.58 mL | 83.15 mL |
| 0.5 mM | 1.66 mL | 8.32 mL | 16.63 mL |
| 1 mM | 0.83 mL | 4.16 mL | 8.32 mL |
| 5 mM | 0.17 mL | 0.83 mL | 1.66 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2