CYT997 (Lexibulin)

目录号: A10264

Microtubule Inhibitor

CYT997 (Lexibulin) Chemical Structure

CAS NO. 917111-44-5

CYT997 is a novel anti-cancer vascular disrupting agent (VDA). In vitro, CYT997 is shown to potently inhibit the proliferation of vascular endothelial growth factor-stimulated human umbilical vein endothelial cells (IC(50) 3.7 ± 1.8 nM) and cause significant morphological changes at 100 nM, including membrane blebbing.

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,400.00
50 mg
¥ 4,000.00
100 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 1,290.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

CYT997 is a novel anti-cancer vascular disrupting agent (VDA). In vitro, CYT997 is shown to potently inhibit the proliferation of vascular endothelial growth factor-stimulated human umbilical vein endothelial cells (IC(50) 3.7 ± 1.8 nM) and cause significant morphological changes at 100 nM, including membrane blebbing.
靶点信息
Microtubules (cancer cell lines)
10 nM-100 nM
In vitro DMSO 86 mg/mL (197.91 mM)
Water <1 mg/mL (<1 mM)
Ethanol 20 mg/mL (46.02 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.01 mL 115.07 mL 230.15 mL
0.5 mM 4.6 mL 23.01 mL 46.03 mL
1 mM 2.3 mL 11.51 mL 23.01 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10264
MECHANISM OF ACTION Inhibitor
M. Wt 434.5
Formula C24H30N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 917111-44-5
Synonyms CYT-997, Lexibulin
SMILES CCC[C@@H](C1=CN=CC=C1)NC2=NC(=NC=C2C)C3=CC(=C(C=C3)NC(=O)NCC)OC

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