Cytarabine
目录号: A10265
Cytarabine 通过整合到 DNA 中来抑制 DNA 复制（在 L1210 和 CEM 细胞系中的 IC50 = 0.04 μM）。
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生物活性
| Discription | Cytarabine inhibits DNA replication by incorporating into DNA (IC50 = 0.04 μM in L1210 and CEM cell lines). | ||
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产品信息
| 目录号 | A10265 |
|---|---|
| 分子式 | C9H13N3O5 |
| 分子量 | 243.2 |
| CAS号 | 147-94-4 |
| SMILES | C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O |
| 其他名称 | Cytosine b-D-arabinofuranoside, cytosine arabinoside, Ara-C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 1 mg/mL (4.11 mM) | |
| Water | 41 mg/mL (168.57 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | Saline | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 41.12 mL | 205.59 mL | 411.18 mL |
| 0.5 mM | 8.22 mL | 41.12 mL | 82.24 mL |
| 1 mM | 4.11 mL | 20.56 mL | 41.12 mL |
| 5 mM | 0.82 mL | 4.11 mL | 8.22 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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