CZC24832

目录号: A11363

PI3K inhibitor

CZC24832

CZC24832 Chemical Structure

CAS NO. 1159824-67-5

CZC24832 is a selective inhibitor of PI 3-Kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,400.00
25 mg
¥ 2,800.00
50 mg
¥ 4,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

CZC24832 is a selective inhibitor of PI 3-Kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).
Targets
PI3Kγ PI3Kβ PI3Kδ
27 nM1.1 μM8.2 μM
In vitro (25°C) DMSO 5 mg/mL heating (13.72 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.44 mL 137.21 mL 274.42 mL
0.5 mM 5.49 mL 27.44 mL 54.88 mL
1 mM 2.74 mL 13.72 mL 27.44 mL
5 mM 0.55 mL 2.74 mL 5.49 mL

*The above data is based on the productmolecular weight 364.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11363
MECHANISM OF ACTION Inhibitor
M. Wt 364.4
Formula C15H17FN6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1159824-67-5
Synonyms CZC 24832, CZC-24832
SMILES CC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)F

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