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PI3K 抑制剂

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产品目录号: A11363


产品名 目录号 价格 数量
CZC24832 5mg A11363-5
¥ 800.00
CZC24832 10mg A11363-10
¥ 1,400.00
CZC24832 25mg A11363-25
¥ 2,800.00
CZC24832 50mg A11363-50
¥ 4,800.00



CZC24832 is a selective inhibitor of PI 3-Kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 CZC24832 发表的文献 (1)
  • Yoshihiro Umezawa, .et al. Molecular mechanisms for enhancement of stromal cell-derived factor 1每induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1), J Biol Chem, 2017, Dec 1; 292(48): 19639每19655 PMID: 28974577

Chemical Information

目录号 A11363
Mechanism of action Inhibitor
分子量 364.4
化学分子式 C15H17FN6O2S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1159824-67-5
Synonyms CZC 24832, CZC-24832
SMILES code CC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)F
化学名称 5-(2-Amino-8-fluoro[1,2,4]triazolo[?1,5-a]pyridin-6-yl)-N-(1,1-dimethylethyl)-3-pyridi?nesulfonamide


CZC24832 is a selective inhibitor of PI 3-Kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).
27 nM1.1 μM8.2 μM


Solubility (25°C) * In vitro DMSO 5 mg/mL heating (13.72 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.44 mL 137.21 mL 274.42mL
0.5 mM 5.49 mL 27.44 mL 54.88 mL
1 mM 2.74 mL 13.72 mL 27.44 mL
5 mM 0.55 mL 2.74 mL 5.49 mL

*The above data is based on the productmolecular weight 364.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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