CZC24832

Name: CZC24832
SKU: A11363
Price: 245 CNY
Rating: 5 (2 reviews)

目录号: A11363

PI3K 抑制剂

2 篇发表文献

CZC24832 是一种选择性的 PI 3-激酶γ抑制剂（在 PI 3-Kγ依赖的 fMLP 诱导的中性粒细胞迁移实验中，IC50 = 1.0 μM）。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
2mg	¥385.00	现货
5mg	¥525.00	现货
10mg	¥945.00	现货
25mg	¥1,715.00	现货
50mg	¥2,590.00	现货
100mg	¥3,815.00	现货
*10mM 1mL in DMSO**	¥735.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用CZC24832发表的2篇文献

Kevin J Pridham, .et al. , iScience, 2024, May 7;27(6):109921 PMID: 38812542

Yoshihiro Umezawa, .et al. , J Biol Chem, 2017, Dec 1; 292(48): 19639-19655 PMID: 28974577

生物活性

Discription

CZC24832 is a selective inhibitor of PI 3-Kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).

Targets

Target	Value

产品信息

目录号	A11363
分子式	C15H17FN6O2S
分子量	364.4
CAS号	1159824-67-5
SMILES	CC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)F
其他名称	CZC 24832, CZC-24832
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 5 mg/mL (13.72 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.44 mL	137.21 mL	274.42 mL
0.5 mM	5.49 mL	27.44 mL	54.88 mL
1 mM	2.74 mL	13.72 mL	27.44 mL
5 mM	0.55 mL	2.74 mL	5.49 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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