Dabrafenib Mesylate

目录号: A15059

Raf inhibitor

Dabrafenib Mesylate Chemical Structure

CAS NO. 1195768-06-9

Dabrafenib Mesylate is a novel, potent, and selective Raf kinase inhibitor that is capableof inhibiting the kinase activity of wild-type B-Raf, B-RafV600Eand c-Raf with IC50 values of 3.2, 0.8, and 5.0 nM, respectively.

库存: 现货

规格 价格 数量
10 mg
¥ 600.00
50 mg
¥ 900.00
100 mg
¥ 1,260.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Dabrafenib Mesylate is a novel, potent, and selective Raf kinase inhibitor that is capableof inhibiting the kinase activity of wild-type B-Raf, B-RafV600Eand c-Raf with IC50 values of 3.2, 0.8, and 5.0 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.24 mL 81.21 mL 162.42 mL
0.5 mM 3.25 mL 16.24 mL 32.48 mL
1 mM 1.62 mL 8.12 mL 16.24 mL
5 mM 0.32 mL 1.62 mL 3.25 mL

*The above data is based on the productmolecular weight 615.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15059
MECHANISM OF ACTION Inhibitor
M. Wt 615.67
Formula C24H24F3N5O5S3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1195768-06-9
Synonyms GSK-2118436 Mesylate, GSK2118436 Mesylate, GSK 2118436 Mesylate, GSK 2118436B
SMILES CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F.CS(=O)(=O)O

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