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Dacarbazine是一种用于治疗各种癌症的抗肿瘤化学治疗药物。Dacarbazine是烷基化剂类别的成员，其通过向其DNA中添加烷基（CnH2n+1）来破坏癌细胞。
靶点信息
| Nucleoside antimetabolite/analog | ||||
| In vitro (25°C) | DMSO | Warmed: 12 mg/mL (65.86 mM) | |
| Water | Warmed: 2 mg/mL (10.97 mM) | ||
| Ethanol | Warmed: 1 mg/mL (5.48 mM) | ||
| In vivo | 0.5% CMC Na | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 54.89 mL | 274.45 mL | 548.91 mL |
| 0.5 mM | 10.98 mL | 54.89 mL | 109.78 mL |
| 1 mM | 5.49 mL | 27.45 mL | 54.89 mL |
| 5 mM | 1.1 mL | 5.49 mL | 10.98 mL |
*The above data is based on the productmolecular weight 182.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10281 |
|---|---|
| M. Wt | 182.18 |
| Formula | C6H10N6O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | CAS: 4342-03-4 |
| Synonyms | DTIC |
| SMILES | CN(C)N/N=C/1\C(=NC=N1)C(=O)N |
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