Dacetuzumab (SGN-40) is a humanized IgG1 monoclonal antibody targeting CD40, demonstrating potent anti-lymphoma properties. This therapeutic antibody exerts its effects through immune effector functions, including antibody-dependent cellular cytotoxicity and phagocytosis (ADCC/ADCP), leading to the effective elimination of tumor cells. Dacetuzumab is primarily utilized in research focused on multiple myeloma, offering significant insights into disease mechanisms and potential therapeutic strategies.
Dacetuzumab (SGN-40) is a humanized IgG1 monoclonal antibody targeting CD40, demonstrating potent anti-lymphoma properties. This therapeutic antibody exerts its effects through immune effector functions, including antibody-dependent cellular cytotoxicity and phagocytosis (ADCC/ADCP), leading to the effective elimination of tumor cells. Dacetuzumab is primarily utilized in research focused on multiple myeloma, offering significant insights into disease mechanisms and potential therapeutic strategies.
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